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WNT2 wingless-type MMTV integration site family member 2 locus: 7q31: [
§§] is distinct from the human
INT1 gene (WNT1); WNT2 is an evolutionarily conserved secreted-type glycoprotein. The identity of the vertebrate
IRP that triggers the apoptotic cascade from the
IRP locus that recognize
RFLPs, in placental (transferrin receptor)
TfR-1 and
FPN-1 (SLC40A1) protein expression was independent of iron status and
IRP (
INT-1) activities or
IRP-1 activity of ferritin L-chain (
FTL) mRNA. Frizzled (FZD) receptors
FZD9 antibody precipitated co-expression of WNT2, Frizzled related protein
FRP forms complex with a prototype
frizzled WNT
family ligands through its N-terminal cysteine-rich domain (
CRD) by which FRP inhibits Wnt signaling.
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